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human granulosa cell tumor cell line kgn  (Procell Inc)

 
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    Procell Inc human granulosa cell tumor cell line kgn
    Human Granulosa Cell Tumor Cell Line Kgn, supplied by Procell Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+granulosa+tumor+cell+line+kgn/3+ov+sk/pmc12487243-85-1-10
    Average 86 stars, based on 1 article reviews
    human granulosa cell tumor cell line kgn - by Bioz Stars, 2026-09
    86/100 stars

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    other:

    Article Title: SFRP4 contributes to insulin resistance-induced polycystic ovary syndrome by triggering ovarian granulosa cell hyperandrogenism and apoptosis through the nuclear β-catenin/IL-6 signaling axis.
    Article Snippet: Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by chronic ovulation dysfunction and overproduction of androgens.. Women with PCOS are commonly accompanied by insulin resistance (IR), which can impair insulin sensitivity and elevate blood glucose levels.. IR promotes ovarian cysts, ovulatory dysfunction, and menstrual irregularities in women patients, leading to the pathogenesis of PCOS.



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    Effect of endometriotic cells on the expression of folliculogenesis-related genes in granulosa cells in vitro. The AMH ( A ), AMHR2 ( B ), KITLG ( C ), and MTOR ( D ) mRNA expressions were assessed in KGN granulosa cells by RT-qPCR. KGN cells were cultured alone (KGN) or co-cultured with 12Z endometriotic cells (KGN + 12Z) for 48 h. 18S or RPLP0 were used as housekeeping genes. Results are expressed as means ± SEM. n is expressed in parentheses in each bar. Statistical comparisons were performed by Student’s “ t ” test. * p < 0.05 KGN vs. KGN + 12Z.

    Journal: Biomedicines

    Article Title: Peritoneal Endometriosis Impairs Ovarian Reserve and Increases Atresia in a Rat Model

    doi: 10.3390/biomedicines13020348

    Figure Lengend Snippet: Effect of endometriotic cells on the expression of folliculogenesis-related genes in granulosa cells in vitro. The AMH ( A ), AMHR2 ( B ), KITLG ( C ), and MTOR ( D ) mRNA expressions were assessed in KGN granulosa cells by RT-qPCR. KGN cells were cultured alone (KGN) or co-cultured with 12Z endometriotic cells (KGN + 12Z) for 48 h. 18S or RPLP0 were used as housekeeping genes. Results are expressed as means ± SEM. n is expressed in parentheses in each bar. Statistical comparisons were performed by Student’s “ t ” test. * p < 0.05 KGN vs. KGN + 12Z.

    Article Snippet: In this study, we used the immortalized human epithelial-like endometriotic cell line 12Z [ ] and the human granulosa tumor cell line KGN (RIKEN Bioresource Centre, Tsukuba, Japan).

    Techniques: Expressing, In Vitro, Quantitative RT-PCR, Cell Culture

    KA3D had no effect on KGN ovarian granulosa cells

    Journal: BMC Cancer

    Article Title: A quinoline-2-thione derivative as a novel chemotherapy drug candidate displays anti-tumor activity in vitro and in vivo

    doi: 10.1186/s12885-024-13042-7

    Figure Lengend Snippet: KA3D had no effect on KGN ovarian granulosa cells

    Article Snippet: The human granulosa cell line KGN (fibroblast-like granulosa cell tumor) was obtained from Procell Co., Ltd. (Wuhan, China).

    Techniques: